RECOMBINANT HUMAN

ALBUMIN

IDENTIFICATION AND USE: Genetically engineered human albumin derived from yeast. Currently, only the MMR vaccine contains genetically engineered human protein, which is produced under the brand name recombumin and referred to as “recombinant human albumin” in the package insert.

HUMAN EXPOSURE/TOXICITY: Albumin (human) is used for treating a variety of conditions, including shock due to blood loss in the body, burns, low protein levels due to surgery or liver failure, and as an additional medicine in bypass surgery. Albumin (human) is a concentrate of plasma proteins from human blood. It works by increasing plasma volume or serum albumin levels.

ADVERSE EFFECTS: anaphylactoid reactions, fever, chills, rash, nausea, vomiting, tachycardia.

DERMATOLOGIC SIDE EFFECTS: urticaria, skin rash, pruritus, edema, and erythema.

NERVOUS SYSTEM SIDE EFFECTS: headache, chills, and febrile reactions.

CARDIOVASCULAR SIDE EFFECTS: hypotension.

GASTROINTESTINAL SIDE EFFECTS: nausea, vomiting and increased salivation.

RESPIRATORY SIDE EFFECTS: bronchospasm.

FOUND IN THE FOLLOWING VACCINES: MMR (MMR-II)