VACCINE USAGE: TWINRIX is a vaccine indicated for active immunization against disease caused by hepatitis A virus and infection by all known subtypes of hepatitis B virus. TWINRIX is approved for use in persons 18 years of age or older.

VACCINE DOSAGE: TWINRIX is administered by intramuscular injection.

  • Standard Dosing: A series of 3 doses (1 mL each) given on a 0-, 1-, and 6-month schedule.
  • Accelerated Dosing: A series of 4 doses (1 mL each) given on days 0, 7, and 21 to 30 followed by a booster dose at month 12.

VACCINE INGEDIENTS: formalin, yeast protein, aluminum phosphate, aluminum hydroxide, amino acids, phosphate buffer, polysorbate 20, neomycin sulfate, MRC-5 human diploid cells.

ADVERSE VACCINE REACTIONS: headache, fatigue, diarrhea, nausea, fever, vomiting, upper respiratory tract infection, anorexia, agitation, insomnia, dizziness, migraine, paresthesia, somnolence, syncope, vertigo, erythema, rash, sweating, back pain, myalgia, lymphadenopathy, dysgeusia, photophobia, hypotension, herpes zoster, meningitis, Bell’s palsy, convulsions, Guillain-Barre syndrome, multiple sclerosis, neuritis, earaches, tinnitus, palpitations, hepatitis, jaundice, eczema, lichen planus, arthritis, chills.