VACCINE USAGE: Pentacel is a vaccine indicated for active immunization against diphtheria, tetanus, pertussis, poliomyelitis and invasive disease due to Haemophilus influenzae type b. Pentacel is approved for use as a four-dose series in children 6 weeks through 4 years of age (prior to 5th birthday).

VACCINE DOSAGE: The four dose immunization series consists of a 0.5-mL intramuscular injection, after reconstitution, administered at 2, 4, 6 and 15-18 months of age.

Pentacel consists of a liquid vaccine component (DTaP-IPV component) and a lyophilized vaccine component (ActHIB vaccine). Reconstitute the ActHIB vaccine component with the DTaP-IPV component immediately before administration.

VACCINE INGEDIENTS: aluminum phosphate, polysorbate 80, formaldehyde, glutaraldehyde, bovine serum albumin, 2-phenoxyethanol, neomycin, polymyxin B sulfate, Mueller’s growth medium, Mueller-Miller casamino acid medium (without beef heart infusion), Stainer-Scholte medium (modified by the addition of casamino acids and dimethyl-beta-cyclodextrin), MRC-5 (human diploid) cells, CMRL 1969 medium (supplemented with calf serum), ammonium sulfate, medium 199.

ADVERSE VACCINE REACTIONS: dehydration, gastroenteritis, asthma, pneumonia, death due to suffocation, head trauma, sudden infant death syndrome (SIDS), neuroblastoma, cyanosis, vomiting, nausea, meningitis, rhinitis, viral infection, decreased appetite, depressed level of consciousness, screaming, apnea, cough, erythema, skin discoloration, pallor.